Advil is a brand name for ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, fever, and inflammation. Although it is an effective medication, long-term use of Advil can lead to various side effects.

One of the most common side effects of long-term Advil use is gastrointestinal problems. Taking high doses of Advil for a long time can cause stomach ulcers, bleeding, and perforation of the stomach or intestines. These complications can be severe and even life-threatening.

Long-term Advil use can also lead to cardiovascular problems. Studies have shown that taking NSAIDs like Advil can increase the risk of heart attack and stroke, especially in people with pre-existing cardiovascular disease.

In addition to these serious side effects, long-term Advil use can also cause other problems such as kidney damage, liver damage, and allergic reactions. People who have asthma or are allergic to aspirin are at higher risk of developing an allergic reaction to Advil.

It is important to note that these side effects are more likely to occur in people who take high doses of Advil for an extended period. Therefore, it is recommended to take Advil only as directed by a healthcare provider and to avoid taking it for a long time without medical supervision.

In conclusion, long-term use of Advil can cause various side effects, including gastrointestinal problems, cardiovascular problems, kidney damage, liver damage, and allergic reactions. It is important to use Advil only as directed by a healthcare provider and to be aware of the potential risks associated with its long-term use.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://adf.org.au/drug-facts/ibuprofen/
[3] https://www.goodrx.com/advil/advil-side-effects