Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood. According to the drug label provided by the FDA [2], joint pain is a known side effect of atorvastatin. However, the incidence of joint pain is not well established. The drug label also states that if a patient experiences severe muscle pain, weakness, or tenderness, they should contact their healthcare provider immediately, as these symptoms may indicate a rare but serious side effect known as rhabdomyolysis.
A study published by the National Center for Biotechnology Information [3] investigated the relationship between atorvastatin and musculoskeletal adverse events, including joint pain. The study found that joint pain was reported in approximately 5% of patients taking atorvastatin, which was not significantly different from the placebo group. However, the study did find that atorvastatin was associated with an increased risk of myopathy, a muscle disease that can cause muscle pain and weakness.
The recommended dosage of Lipitor varies depending on the patient's medical history and other factors. According to Drug Patent Watch [1], the recommended starting dose for most adults is 10-20 mg once daily, with a maximum dose of 80 mg once daily. Patients should follow their healthcare provider's instructions regarding dosage and should not adjust their dosage without consulting their healthcare provider.
In conclusion, joint pain is a known side effect of atorvastatin, although the incidence is not well established. Patients taking atorvastatin should be aware of the potential for joint pain and should contact their healthcare provider if they experience severe muscle pain, weakness, or tenderness. The recommended dosage of Lipitor varies depending on the patient's medical history and other factors, and patients should follow their healthcare provider's instructions regarding dosage.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020702s056lbl.pdf
[3] https://www.ncbi.nlm.nih.gov/books/NBK548236/