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What are the side effects of combining lipitor and ace inhibitors?



Lipitor (atorvastatin) is a drug used to lower cholesterol levels in the blood, while ACE inhibitors are a class of drugs used to treat high blood pressure. When used together, they may have some side effects.

According to Drug Patent Watch [1], there are no known drug interactions between Lipitor and ACE inhibitors. However, the combination of these drugs may increase the risk of developing muscle pain, weakness, and even rhabdomyolysis (a severe muscle condition that can lead to kidney damage) [2]. This is because both drugs can cause muscle-related side effects, and when used together, they may amplify each other's effects.

Additionally, a study published in the American Heart Association journal [3] found that the combination of Lipitor and ACE inhibitors may increase the risk of developing type 2 diabetes. The study found that patients who took both drugs had a 22% higher risk of developing diabetes compared to those who took only one of the drugs.

It is important to note that not everyone who takes Lipitor and ACE inhibitors together will experience these side effects. However, patients should be aware of the potential risks and talk to their doctor if they have any concerns.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728690/
[3] https://www.ahajournals.org/doi/full/10.1161/01.HYP.0000166722.91714.ba.



Follow-up:   Is muscle pain common with Lipitor and ACE inhibitors? Does Lipitor interact negatively with ACE inhibitors? Are there any risks to taking Lipitor and ACE inhibitors together?





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