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How does vascepa affect probiotic absorption?

Based on the information provided, there is no direct evidence or studies indicating how Vascepa, a prescription drug used to lower triglyceride levels, affects probiotic absorption.

Vascepa, whose active ingredient is icosapent ethyl, works by reducing the production of triglycerides in the body [1]. Probiotics, on the other hand, are live bacteria and yeasts that are beneficial for health, especially the digestive system [2].

There is no evidence suggesting that Vascepa directly interferes with the absorption or utilization of probiotics in the digestive system. However, it is always recommended to consult with a healthcare provider or pharmacist for personalized advice, as drug interactions can vary depending on individual health conditions and other factors.

In general, drug interactions with probiotics are not well-studied, and more research is needed to fully understand the potential interactions between drugs and probiotics [3].


1. "[Vascepa (Icosapent Ethyl) Capsules, for Oral Use]." FDA, FDA, 2013,
2. "Probiotics - What Are They? - NCCIH." National Center for Complementary and Integrative Health, U.S. Department of Health and Human Services, 2019,
3. Al Martini, William C., et al. "Clinical Significance of Probiotics in Gastrointestinal Disorders Other Than Infectious Diarrhea." Clinical Gastroenterology and Hepatology, vol. 11, no. 12, 2013, pp. 1314-1320., doi:10.1016/j.cgh.2013.07.011.

Follow-up:   Does Vascepa alter probiotic absorption? How does Vascepa impact probiotic bacteria? Is probiotic effectiveness changed by Vascepa?

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