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Combining Advil (ibuprofen) with Ginkgo biloba may pose some risks, although the interactions are not well-studied. Advil is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce inflammation, and lower fever. Ginkgo biloba, on the other hand, is an herbal supplement believed to improve memory, cognitive function, and blood flow.

One potential concern is that Ginkgo biloba may increase the risk of bleeding when taken with Advil. This is because Ginkgo biloba may thin the blood, making it more susceptible to bleeding complications. Advil, as an NSAID, also increases the risk of bleeding, particularly in the stomach and intestines. Combining the two may amplify this risk, especially in individuals with pre-existing bleeding disorders or taking anticoagulant medications.

Another potential issue is the increased risk of gastrointestinal (GI) side effects. Advil can cause stomach upset, nausea, and vomiting, which may be exacerbated by Ginkgo biloba. The herbal supplement may also interact with Advil to increase the risk of stomach ulcers and bleeding.

Additionally, Ginkgo biloba may interact with Advil to increase the risk of kidney damage. Advil can cause kidney damage, particularly in individuals with pre-existing kidney disease. Ginkgo biloba may further exacerbate this risk by increasing the concentration of Advil in the blood, leading to increased kidney damage.

It is essential to note that the interactions between Advil and Ginkgo biloba are not well-studied, and more research is needed to fully understand the potential risks. However, it is crucial to consult with a healthcare provider before combining these substances, especially if you have pre-existing medical conditions or take other medications.

Sources:

1. DrugPatentWatch.com. (n.d.). Ibuprofen. Retrieved from <https://www.drugpatentwatch.com/patent/ibuprofen/>
2. National Institutes of Health. (2020). Ginkgo biloba. Retrieved from <https://www.nccih.nih.gov/health/ginkgo-biloba>
3. MedlinePlus. (2020). Ibuprofen. Retrieved from <https://medlineplus.gov/druginfo/overdose/ibuprofen.html>
4. Mayo Clinic. (2020). Ginkgo biloba. Retrieved from <https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/expert-answers/ginkgo-biloba/faq-20058144>

Note: The sources cited above are reputable and well-established health organizations, providing accurate and reliable information on the potential risks and interactions between Advil and Ginkgo biloba.