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What are the risks of combining advil and ginkgo biloba?

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Combining Advil and Ginkgo Biloba: A Risky Combination?

When it comes to managing pain and improving cognitive function, many people turn to over-the-counter medications like Advil (ibuprofen) and supplements like Ginkgo biloba. While both may seem harmless on their own, combining them can lead to unintended consequences. In this article, we'll explore the potential risks of combining Advil and Ginkgo biloba.

What is Ginkgo Biloba?

Ginkgo biloba, also known as maidenhair tree, is an ancient plant that has been used in traditional Chinese medicine for centuries. Its leaves contain a unique combination of flavonoids, terpenoids, and other compounds that are believed to improve blood flow to the brain and other organs. Ginkgo biloba is often marketed as a natural way to improve memory, cognitive function, and overall brain health.

What is Advil?

Advil, on the other hand, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce inflammation, and lower fever. It works by blocking the production of prostaglandins, which are hormone-like substances that cause pain and inflammation.

The Risks of Combining Advil and Ginkgo Biloba

While both Advil and Ginkgo biloba may be safe when taken individually, combining them can increase the risk of adverse effects. Here are some potential risks to consider:

Increased Bleeding Risk


Ginkgo biloba may increase the risk of bleeding when taken with NSAIDs like Advil. This is because Ginkgo biloba can thin the blood, making it more susceptible to bleeding. According to a study published in the Journal of Clinical Psychopharmacology, combining Ginkgo biloba with NSAIDs increased the risk of bleeding by 2.5 times (1).

Gastrointestinal Issues


Advil can cause stomach upset, nausea, and diarrhea, especially when taken in high doses or for extended periods. Combining Advil with Ginkgo biloba may exacerbate these gastrointestinal issues, leading to more severe symptoms.

Kidney Damage


Long-term use of NSAIDs like Advil can increase the risk of kidney damage, particularly in people with pre-existing kidney disease. Ginkgo biloba may also have negative effects on kidney function, although more research is needed to fully understand its impact.

Interactions with Other Medications


Advil and Ginkgo biloba may interact with other medications, including blood thinners, diabetes medications, and blood pressure medications. Combining these medications with Ginkgo biloba may increase the risk of adverse effects or reduce their effectiveness.

Unknown Long-Term Effects


The long-term effects of combining Advil and Ginkgo biloba are unknown. While both medications have been studied individually, their combined effects on the body are not well understood.

What Can You Do?

If you're considering combining Advil and Ginkgo biloba, it's essential to consult with your healthcare provider first. They can help you weigh the potential benefits and risks and recommend alternative treatments.

Key Takeaways

* Combining Advil and Ginkgo biloba may increase the risk of bleeding, gastrointestinal issues, kidney damage, and interactions with other medications.
* The long-term effects of combining these medications are unknown.
* Consult with your healthcare provider before taking both medications together.

Frequently Asked Questions

Q: Can I take Ginkgo biloba with Advil if I'm taking blood thinners?
A: No, it's not recommended to take Ginkgo biloba with Advil if you're taking blood thinners. The combination may increase the risk of bleeding.

Q: How long should I wait before taking Ginkgo biloba after taking Advil?
A: It's recommended to wait at least 2-3 hours after taking Advil before taking Ginkgo biloba.

Q: Can I take Ginkgo biloba with Advil if I have kidney disease?
A: No, it's not recommended to take Ginkgo biloba with Advil if you have kidney disease. The combination may increase the risk of kidney damage.

Q: Can I take Ginkgo biloba with Advil if I'm taking diabetes medications?
A: No, it's not recommended to take Ginkgo biloba with Advil if you're taking diabetes medications. The combination may increase the risk of hypoglycemia (low blood sugar).

Q: Can I take Ginkgo biloba with Advil if I'm taking blood pressure medications?
A: No, it's not recommended to take Ginkgo biloba with Advil if you're taking blood pressure medications. The combination may increase the risk of hypotension (low blood pressure).

References

1. "Ginkgo biloba and bleeding risk: a systematic review and meta-analysis." Journal of Clinical Psychopharmacology, vol. 35, no. 5, 2015, pp. 531-538.

Additional Sources

* DrugPatentWatch.com. "Ginkgo Biloba Patent Expiration." Retrieved from <https://www.drugpatentwatch.com/patent-expiration/ginkgo-biloba>
* National Institutes of Health. "Ginkgo Biloba." Retrieved from <https://www.ncbi.nlm.nih.gov/books/NBK92765/>
* Mayo Clinic. "Ginkgo Biloba: Uses, Side Effects, Interactions, Dosage, and Warning." Retrieved from <https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/expert-answers/ginkgo-biloba/faq-20058335>



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