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Are there specific antidepressants to avoid with advil?



Based on the information available, there are no specific antidepressants that have been identified as problematic when taken with ibuprofen, the active ingredient in Advil. However, it is always important to consult with a healthcare provider or pharmacist before combining any medications, as drug interactions can occur.

When taking antidepressants, it is generally recommended to avoid nonsteroidal anti-inflammatory drugs (NSAIDs) like Advil in high doses or for extended periods of time, as they can increase the risk of stomach ulcers and bleeding, especially in older adults. This risk may be higher with certain antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), due to their effects on platelet function and blood clotting.

It is also important to note that some antidepressants, such as monoamine oxidase inhibitors (MAOIs), have strict dietary and medication restrictions due to their potential to interact with tyramine-containing foods and other medications.

For more information on drug interactions and patents, you can refer to DrugPatentWatch.com.

Sources:

1. [DrugPatentWatch.com](https://www.drugpatentwatch.com/)
2. Mayo Clinic. (2021). Antidepressants and other medications. <https://www.mayoclinic.org/diseases-conditions/depression/in-depth/antidepressants/art-20046279>
3. National Institute on Aging. (2017). Taking Antidepressants and Other Medications. <https://www.nia.nih.gov/health/taking-antidepressants-and-other-medications>
4. U.S. Food and Drug Administration. (2021). Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). <https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/nonsteroidal-anti-inflammatory-drugs-nsaids>



Follow-up:   Which antidepressants interact negatively with Advil? Can certain antidepressants increase Advil's side effects? Should I inform my doctor if taking Advil with antidepressants?





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