Lipitor is a medication used to lower cholesterol levels in the blood. It belongs to a class of drugs called statins. Potassium-based salt substitutes are often used as a dietary supplement to manage high blood pressure. When these two substances are taken together, there is a potential for drug interactions.

According to DrugPatentWatch [1], there is no known interaction between Lipitor and potassium-based salt substitutes. However, it is important to note that this does not mean that interactions cannot occur.

The US Pharmacist [2] states that there is a possibility that taking potassium supplements or potassium-based salt substitutes with Lipitor can increase the risk of muscle problems, such as myopathy or rhabdomyolysis. This is because both Lipitor and potassium supplements can cause an increase in potassium levels in the blood, which can be dangerous.

Drugs.com [3] also warns that taking Lipitor with losartan, a medication commonly used to treat high blood pressure, can increase the risk of muscle problems. Losartan can increase the levels of Lipitor in the blood, which can lead to an increased risk of side effects.

In conclusion, while there is no known interaction between Lipitor and potassium-based salt substitutes, there is a potential for increased risk of muscle problems when taking potassium supplements or potassium-based salt substitutes with Lipitor. It is important to talk to a healthcare provider before taking any new supplements or medications to avoid potential drug interactions.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.uspharmacist.com/article/drug-interactions-with-vitamins-and-minerals
[3] https://www.drugs.com/drug-interactions/lipitor-with-losartan-276-128-1489-0.html