Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. According to the NHS [2], it is recommended to take atorvastatin once a day, preferably in the evening, with or without food. It is important to take atorvastatin at the same time every day to maintain a consistent level of the medication in the body.

While it is not necessary to take atorvastatin with food, doing so may help reduce the risk of stomach upset [3]. However, it is important to avoid consuming grapefruit or grapefruit juice while taking atorvastatin as it can increase the risk of side effects [3].

In summary, it is recommended to take atorvastatin once a day, preferably in the evening, with or without food [2]. While taking it with food may help reduce the risk of stomach upset, it is important to avoid consuming grapefruit or grapefruit juice while taking atorvastatin [3].

Sources:
[2] https://www.nhs.uk/medicines/atorvastatin/how-and-when-to-take-atorvastatin/
[3] https://www.drugs.com/medical-answers/eat-food-taking-atorvastatin-3565628/
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR