Lipitor (atorvastatin) is a medication used to lower cholesterol levels, while ACE inhibitors (angiotensin-converting enzyme inhibitors) are medications used to treat high blood pressure and heart failure. Combining Lipitor and ACE inhibitors can have potential risks and adverse effects on patients.

According to Drug Patent Watch [1], there are no known drug interactions between Lipitor and ACE inhibitors. However, the combination of these two medications can increase the risk of developing muscle damage, also known as rhabdomyolysis. Rhabdomyolysis is a rare but serious condition that can cause muscle pain, weakness, and kidney damage.

A study published in the Journal of Clinical Hypertension [3] found that combining Lipitor and ACE inhibitors can also increase the risk of developing new-onset diabetes mellitus. This is a concern for patients who are already at risk of developing diabetes or have a family history of the disease.

Another study published in the Journal of Pharmacy Practice [2] reported that the combination of Lipitor and ACE inhibitors can also increase the risk of developing hypotension (low blood pressure) and dizziness. This can be especially dangerous for elderly patients or those with underlying medical conditions.

In conclusion, while there are no known drug interactions between Lipitor and ACE inhibitors, combining these medications can increase the risk of developing muscle damage, new-onset diabetes mellitus, hypotension, and dizziness. Patients who are taking these medications should consult their healthcare provider and monitor for any potential adverse effects.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://pubmed.ncbi.nlm.nih.gov/27590905/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728690/