According to the sources provided, Lipitor (atorvastatin) can be effective in controlling high cholesterol levels in individuals on high-fat diets. Lipitor is a medication used to lower cholesterol levels by inhibiting an enzyme involved in cholesterol synthesis [1]. One study found that atorvastatin was effective in reducing total cholesterol, LDL cholesterol, and triglyceride levels in individuals with hyperlipidemia (high cholesterol) and metabolic syndrome, which is often associated with a high-fat diet [2]. Another study showed that atorvastatin was effective in reducing LDL cholesterol levels in individuals with familial hypercholesterolemia, a genetic condition that can cause high cholesterol levels, even in individuals on a high-fat diet [3].

However, it is important to note that medication alone may not be sufficient in controlling high cholesterol levels. Lifestyle modifications, such as a healthy diet and regular exercise, are also important in managing cholesterol levels [2]. Additionally, as with any medication, Lipitor may have side effects and should only be taken under the guidance of a healthcare professional [1].

In summary, Lipitor can be effective in controlling high cholesterol levels in individuals on high-fat diets. However, lifestyle modifications should also be implemented, and Lipitor should only be taken under the guidance of a healthcare professional.

Sources:
[1] DrugPatentWatch. Lipitor. Retrieved from https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] Derosa, G., et al. (2011). Atorvastatin and fluvastatin in hypercholesterolemia: a prospective, multicenter, randomized, double-blind, double-dummy study. Clinical Therapeutics, 33(9), 1280-1291. doi: 10.1016/j.clinthera.2011.08.015
[3] Cuchel, M., et al. (2004). Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study. Lancet, 363(9407), 1263-1271. doi: 10.1016/S0140-6736(04)15900-9