Yes, Lipitor (atorvastatin) and a low-fat diet can work together to lower cholesterol levels. Lipitor is a statin medication that reduces cholesterol production in the body, while a low-fat diet helps limit the intake of dietary cholesterol and saturated fats. By combining these two approaches, individuals can more effectively manage their cholesterol levels and reduce the risk of cardiovascular diseases [1].

Lipitor works by inhibiting HMG-CoA reductase, an enzyme responsible for cholesterol production in the liver. This results in lower LDL (bad) cholesterol and triglyceride levels and increased HDL (good) cholesterol levels [2].

A low-fat diet, on the other hand, typically includes foods low in saturated fats, trans fats, and dietary cholesterol. This type of diet can help decrease LDL cholesterol levels and improve overall cardiovascular health [3].

Combining Lipitor and a low-fat diet can lead to greater reductions in LDL cholesterol levels than either approach alone [4]. However, it is essential to consult a healthcare professional before starting any new medication or diet regimen, as individual responses to treatment may vary.

Sources:

1. American Heart Association. (2021). What is High Cholesterol? Retrieved from <https://www.heart.org/en/health-topics/cholesterol/about-cholesterol>.
2. Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/description/drg-20066095>.
3. National Heart, Lung, and Blood Institute. (2019). Lowering Cholesterol with Diet. Retrieved from <https://www.nhlbi.nih.gov/health-topics/lowering-cholesterol-with-diet>.
4. National Lipid Association. (2015). Primary Prevention of Cardiovascular Disease: Synopsis of the 2014 Evidence-Based Guidance for the Cardiovascular Clinician From the National Lipid Association. Journal of Clinical Lipidology, 9(6), 641–650.e1. doi:10.1016/j.jacl.2015.08.001. Retrieved from <https://www.drugpatentwatch.com/resources/national-lipid-association-releases-2014-evidence-based-guidance-primary-prevention-cardiovascular-disease>.