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What supplements are safe to take with vascepa?

Vascepa (icosapent ethyl) is a prescription medication used to treat high triglycerides in adults with severe hypertriglyceridemia. While it is generally considered safe when used as directed, it is essential to consult with a healthcare provider before taking any supplements, especially when combining them with Vascepa. Here are some supplements that are considered safe to take with Vascepa, based on available information and expert opinions:

1. Omega-3 fatty acids: As Vascepa is an omega-3 fatty acid derivative, it is essential to note that taking additional omega-3 supplements may not be necessary. However, if you are considering taking omega-3 supplements, it is crucial to consult with your healthcare provider to ensure you are not exceeding the recommended daily intake.
2. Vitamin D: Vitamin D is an essential nutrient that plays a crucial role in maintaining bone health. Taking vitamin D supplements with Vascepa is generally considered safe, as long as you follow the recommended daily intake.
3. Probiotics: Probiotics are beneficial bacteria that can help maintain a healthy gut microbiome. Taking probiotics with Vascepa may help alleviate symptoms of irritable bowel syndrome (IBS) and other gastrointestinal issues.
4. Coenzyme Q10 (CoQ10): CoQ10 is an antioxidant that helps generate energy in cells. Taking CoQ10 supplements with Vascepa may help alleviate symptoms of statin-induced myopathy, a condition characterized by muscle weakness and pain.

It is essential to note that the following supplements may interact with Vascepa or have adverse effects when taken together:

1. Blood thinners: Taking blood thinners, such as warfarin, with Vascepa may increase the risk of bleeding.
2. Diabetes medications: Taking diabetes medications, such as metformin, with Vascepa may increase the risk of hypoglycemia (low blood sugar).
3. Antihypertensive medications: Taking antihypertensive medications, such as beta blockers, with Vascepa may increase the risk of hypotension (low blood pressure).

It is crucial to consult with your healthcare provider before taking any supplements with Vascepa, as they may interact with the medication or have adverse effects. Additionally, it is essential to follow the recommended daily intake and dosage of any supplements to avoid potential interactions.


1. (n.d.). Vascepa (icosapent ethyl). Retrieved from <>
2. National Institutes of Health. (n.d.). Omega-3 fatty acids. Retrieved from <>
3. Mayo Clinic. (n.d.). Vitamin D. Retrieved from <>
4. (n.d.). Probiotics and gut health. Retrieved from <>
5. Healthline. (n.d.). CoQ10: Benefits, Side Effects, and Dosage. Retrieved from <>

Cited sources:

2. National Institutes of Health
3. Mayo Clinic
5. Healthline


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