Advil is a brand name for the drug ibuprofen [1]. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, fever, and inflammation [2]. According to the Mayo Clinic, ibuprofen is generally safe when used as directed, but like any medication, it can cause side effects [3].

Some of the most common side effects of ibuprofen include upset stomach, heartburn, nausea, and vomiting. These side effects are usually mild and go away on their own. However, if you experience severe stomach pain, black or bloody stools, or vomit that looks like coffee grounds, you should seek medical attention immediately [3].

Taking ibuprofen before bed may not have any specific long-term effects, but it is important to follow the recommended dosage and not take more than directed. Overuse of ibuprofen can lead to serious side effects, such as stomach ulcers, kidney damage, and increased risk of heart attack or stroke [2].

It is also important to note that ibuprofen can interact with other medications, including blood thinners, antidepressants, and some high blood pressure medications. It is important to talk to your doctor or pharmacist before taking ibuprofen if you are taking any other medications [3].

In summary, ibuprofen (Advil) is generally safe when used as directed, but like any medication, it can cause side effects. Common side effects include upset stomach, heartburn, nausea, and vomiting. Overuse of ibuprofen can lead to serious side effects, such as stomach ulcers, kidney damage, and increased risk of heart attack or stroke. It is important to follow the recommended dosage and talk to your doctor or pharmacist before taking ibuprofen if you are taking any other medications [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://adf.org.au/drug-facts/ibuprofen/
[3] https://www.mayoclinic.org/drugs-supplements/ibuprofen-oral-route/side-effects/drg-20070602?p=1