Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood and reduce the risk of heart disease and stroke. The question of whether to take Lipitor in the morning or at night is a common one.

According to the National Health Service (NHS) [3], Lipitor can be taken at any time of the day, with or without food. However, the NHS recommends taking it at the same time each day to help remember when to take it.

Drugs.com [2] suggests that taking Lipitor at night may be more effective than taking it in the morning. This is because cholesterol production is highest at night, so taking the medication before bed may help to lower cholesterol levels more effectively. However, the difference in effectiveness between taking Lipitor in the morning or at night is not significant enough to warrant a change in routine for most people.

Drug Patent Watch [1] does not provide any specific guidance on when to take Lipitor.

In summary, Lipitor can be taken at any time of the day, with or without food. Taking it at the same time each day may help with remembering to take the medication. While taking Lipitor at night may be slightly more effective in reducing cholesterol levels, the difference is not significant enough to warrant a change in routine for most people. Ultimately, the best time to take Lipitor will depend on individual preferences and lifestyle.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.drugs.com/medical-answers/does-lipitor-work-better-if-you-take-it-at-night-416127/
[3] https://www.nhs.uk/medicines/atorvastatin/how-and-when-to-take-atorvastatin/