When combining Lipitor (atorvastatin) with pain medications, it is essential to be aware of potential risks. Lipitor is a statin medication used to lower cholesterol levels, and certain pain medications may interact with it. According to the Mayo Clinic, statins like Lipitor can sometimes cause muscle pain or weakness, and combining them with certain pain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, can increase the risk of muscle-related side effects [3]. Additionally, some pain medications, like acetaminophen, can interact with statins and affect liver function, as both are metabolized in the liver [3]. Therefore, it is crucial to consult a healthcare provider before combining Lipitor with any pain medication to ensure safety and minimize the risk of adverse effects.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621682/
[3] https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013