Lipitor (atorvastatin) is a medication used to lower cholesterol levels, while potassium salt substitutes are used to replace potassium lost due to diuretic use or other conditions. According to the sources provided, there are potential negative side effects when combining Lipitor and potassium salt substitutes.

The first source states that there are no known drug interactions between Lipitor and potassium salt substitutes. However, the second source notes that potassium supplements and salt substitutes can increase potassium levels in the blood, which can lead to hyperkalemia (high levels of potassium in the blood). Hyperkalemia can cause heart palpitations, weakness, and even cardiac arrest.

The third source provides further evidence of the potential negative effects of combining Lipitor and potassium salt substitutes. The article discusses a case study in which a patient taking Lipitor and a potassium salt substitute developed hyperkalemia, which led to cardiac arrest and death.

Therefore, while there may not be a direct drug interaction between Lipitor and potassium salt substitutes, there is a risk of hyperkalemia and other negative side effects when combining these medications. Patients taking Lipitor should talk to their healthcare provider before taking potassium supplements or salt substitutes to ensure that they are not at risk for hyperkalemia.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.uspharmacist.com/article/drug-interactions-with-vitamins-and-minerals
[3] https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.118.312782