Lipitor is a brand name for atorvastatin, which is a medication used to lower cholesterol levels in the blood. According to the FDA label for Lipitor [3], grapefruit juice should not be consumed while taking Lipitor, as it can increase the risk of side effects. Grapefruit juice contains compounds that can interfere with the metabolism of Lipitor, leading to higher blood levels of the medication and an increased risk of side effects. Therefore, it is recommended to avoid grapefruit juice and other grapefruit products while taking Lipitor.

Regarding adjusting the Lipitor dosage with grapefruit consumption, there is no evidence to suggest that this is a safe or effective practice. The recommended dosage of Lipitor is determined based on factors such as the patient's age, gender, and medical history, as well as the severity of their condition. Adjusting the dosage without medical supervision can lead to serious health risks and should not be attempted.

In conclusion, grapefruit consumption should be avoided while taking Lipitor, as it can increase the risk of side effects. There is no evidence to suggest that adjusting the Lipitor dosage with grapefruit consumption is safe or effective. It is important to follow the recommended dosage and consult with a healthcare professional before making any changes to the medication regimen.

Sources:
[3] FDA Label for Lipitor: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020702s056lbl.pdf
[2] Harvard Health Publishing: https://www.health.harvard.edu/heart-health/grapefruit-juice-and-statins
[1] Drug Patent Watch: https://www.drugpatentwatch.com/p/tradename/LIPITOR