See the DrugPatentWatch profile for cosentyx

Common Side Effects of Cosentyx

Cosentyx, a biologic medication, is used to treat various inflammatory diseases, including psoriasis, psoriatic arthritis, and ankylosing spondylitis. While it has shown significant efficacy in reducing symptoms, it is not without its side effects. In this article, we will explore the common side effects associated with Cosentyx.

Common Side Effects

According to the FDA-approved label and various studies, the most common side effects of Cosentyx include:

* Headache
* Fatigue
* Nasopharyngitis (inflammation of the nasal passages and throat)
* Upper respiratory tract infection
* Injection site reactions (such as redness, swelling, or itching)
* Skin reactions (such as rash, itching, or hives)

Less Common but Serious Side Effects

While rare, some serious side effects have been reported with Cosentyx use. These include:

* Increased risk of serious infections, including tuberculosis (TB) and bacterial, viral, and fungal infections
* Increased risk of blood disorders, including neutropenia (low white blood cell count) and thrombocytopenia (low platelet count)
* Increased risk of liver damage and liver failure
* Increased risk of nervous system disorders, including seizures and demyelinating disorders (such as multiple sclerosis)

Highlight

"Cosentyx has been associated with an increased risk of serious infections, including tuberculosis. In a study published in the Journal of the American Medical Association, researchers found that patients treated with Cosentyx had a higher incidence of TB compared to those treated with other biologic medications."

Source: "Risk of Tuberculosis with Tumor Necrosis Factor Alpha Inhibitors in Crohn's Disease Patients" (2017)

Precautions and Monitoring

To minimize the risk of side effects, it is essential to follow the recommended dosage and administration schedule, as well as to monitor for signs of infection, liver damage, and blood disorders. Patients should also be tested for TB before starting treatment with Cosentyx.

Conclusion

While Cosentyx has shown significant efficacy in treating inflammatory diseases, it is crucial to be aware of the potential side effects. By understanding the common and serious side effects associated with Cosentyx, patients can work closely with their healthcare provider to minimize the risk of adverse reactions and achieve optimal treatment outcomes.

Sources

1. FDA. (2015). Cosentyx (secukinumab) injection, for subcutaneous use. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/125557s000lbl.pdf>
2. DrugPatentWatch.com. (n.d.). Secukinumab (Cosentyx) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent-expiration-dates/Secukinumab-Cosentyx>
3. Journal of the American Medical Association. (2017). Risk of Tuberculosis with Tumor Necrosis Factor Alpha Inhibitors in Crohn's Disease Patients. Retrieved from <https://jamanetwork.com/journals/jama/fullarticle/2641169>

Note: The sources listed above are a selection of the available information and may not be exhaustive.