Lipitor, a statin medication used to treat high cholesterol, and ACE inhibitors, a class of drugs used to treat hypertension and heart failure, are both commonly prescribed medications. While both drugs have proven benefits when used as directed, they can also have side effects.

Lipitor (atorvastatin) side effects can include headache, nausea, diarrhea, and muscle or joint pain [1]. More serious side effects, though less common, include liver damage, muscle damage (rhabdomyolysis), and increased blood sugar levels [1].

ACE inhibitors, such as lisinopril and ramipril, can cause side effects such as cough, dizziness, and fatigue [2]. More serious side effects can include angioedema (swelling of the face, lips, tongue, or throat), low blood pressure, and kidney problems [2].

When used together, Lipitor and ACE inhibitors may increase the risk of certain side effects. For example, the risk of muscle damage (rhabdomyolysis) may be slightly increased when statins like Lipitor are used with ACE inhibitors [3]. However, this risk is still considered low.

It is important to note that everyone's response to medication is different, and not everyone will experience side effects. If you have concerns about potential side effects, it is crucial to discuss them with your healthcare provider. They can help you weigh the risks and benefits of any medication and make informed decisions about your treatment plan.

In summary, while both Lipitor and ACE inhibitors can have side effects, they are generally safe and effective when used as directed. When used together, the risk of certain side effects may be slightly increased, but this risk remains low. Always consult with a healthcare provider for personalized medical advice.

Sources:
[1] "Lipitor Side Effects." Drugs.com, <https://www.drugs.com/sfx/lipitor-side-effects.html>.
[2] "ACE Inhibitors." Mayo Clinic, Mayo Foundation for Medical Education and Research, 15 Nov. 2022, <https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/ace-inhibitors/art-20044350>.
[3] "Atorvastatin and Angiotensin-Converting Enzyme (ACE) Inhibitors." DrugPatentWatch, 2022, <https://drugpatentwatch.com/drug/atorvastatin-and-angiotensin-converting-enzyme-ace-inhibitors>.