Based on the information provided, I cannot determine the exact speed or timeline of the Lipitor adjustment. However, I can provide some context regarding Lipitor and its patent history.

Lipitor, also known as atorvastatin, is a medication used to treat high cholesterol levels. It was first approved by the FDA in 1996 [1]. The drug was a significant revenue generator for Pfizer, with sales peaking at around $13 billion in 2006 [1].

The first patent for Lipitor expired in 2011 in the United States, which opened the door for generic versions of the drug to enter the market [1]. However, Pfizer had developed a patent strategy that included secondary patents related to the manufacturing process and formulation of Lipitor, which extended its exclusivity until 2017 [1][2].

In response to the patent expiration and the subsequent entry of generic atorvastatin, Pfizer employed various strategies to maintain its market share, such as offering discounts and rebates [1].

In summary, while I cannot provide information on the speed of a specific Lipitor adjustment, I can say that Lipitor's patent expiration in 2011 led to the introduction of generic atorvastatin, and Pfizer implemented various strategies to maintain its position in the market.

Sources:
[1] DrugPatentWatch.com - Lipitor (atorvastatin) Patent Expiration & Generic Entry
<https://www.drugpatentwatch.com/drugs/lipitor>
[2] StatPearls - Atorvastatin
<https://www.ncbi.nlm.nih.gov/books/NBK519505/>