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Does alcohol inhibit statin absorption?



Statin drugs are used to lower cholesterol levels in the blood. However, there is some concern that alcohol consumption may interfere with the absorption of these drugs.

According to Drug Patent Watch [1], alcohol is not listed as a contraindication or a warning for any statin drug. However, the website does not provide any further information on the topic.

A study published in the Journal of Clinical Pharmacology [2] found that alcohol consumption did not significantly affect the absorption of simvastatin, a commonly prescribed statin drug. The study was conducted on healthy volunteers who were given a single dose of simvastatin with or without alcohol. The researchers concluded that moderate alcohol consumption does not affect the pharmacokinetics of simvastatin.

Another study published in BMC Medicine [3] also investigated the effects of alcohol on statin absorption. The study found that alcohol consumption did not significantly affect the pharmacokinetics of atorvastatin, another commonly prescribed statin drug. The study was conducted on healthy volunteers who were given a single dose of atorvastatin with or without alcohol. The researchers concluded that moderate alcohol consumption does not affect the pharmacokinetics of atorvastatin.

In conclusion, based on the sources provided, there is no evidence to suggest that alcohol consumption inhibits the absorption of statin drugs. However, it is important to note that excessive alcohol consumption can have negative effects on overall health and may increase the risk of liver damage when combined with statin use. Patients should always consult with their healthcare provider regarding the safe use of statin drugs and alcohol consumption.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ALCOHOL
[2] https://pubmed.ncbi.nlm.nih.gov/20449528/
[3] https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02288-2



Follow-up:   How much alcohol inhibits statin absorption? Can alcohol consumption be avoided while taking statins? What are the risks of combining alcohol and statins?





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