Based on the information available, there is no definitive answer regarding whether Cosentyx (secukinumab) alters COVID-19 vaccine immunity. However, there are some considerations to take into account.
Cosentyx is a medication used to treat several conditions, including plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis [1]. It is a type of drug called a monoclonal antibody, which works by targeting and blocking a specific molecule in the body called interleukin-17A (IL-17A) [1].
COVID-19 vaccines, such as those from Pfizer-BioNTech and Moderna, work by teaching the immune system how to recognize and fight the SARS-CoV-2 virus [2]. They do this by introducing a small piece of the virus, known as the spike protein, to the body, which triggers an immune response [2].
There is some evidence to suggest that certain medications, such as those that suppress the immune system, may affect the body's response to vaccines [3]. However, it is unclear whether Cosentyx, specifically, has an impact on COVID-19 vaccine immunity.
A study published in the Journal of Allergy and Clinical Immunology found that patients with inflammatory diseases who were taking biologic medications, such as Cosentyx, had a similar immune response to the Pfizer-BioNTech COVID-19 vaccine as those who were not taking these medications [4]. However, the study was small and did not specifically look at Cosentyx.
Therefore, while there is no definitive answer regarding whether Cosentyx alters COVID-19 vaccine immunity, it is important for individuals taking this medication to discuss any concerns with their healthcare provider.
Sources:
1. Cosentyx (secukinumab) [DrugPatentWatch.com]
2. How COVID-19 Vaccines Work [Mayo Clinic]
3. Certain Medications May Affect Immune Response to COVID-19 Vaccines [Johns Hopkins Medicine]
4. Humoral and cellular immune responses to BNT162b2 mRNA COVID-19 vaccine in patients with inflammatory diseases [Journal of Allergy and Clinical Immunology]