Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the body [1]. ACE inhibitors, on the other hand, are medications used to treat high blood pressure by relaxing blood vessels and reducing the workload on the heart [2].

There is limited information available on how Lipitor affects the effectiveness of ACE inhibitors. However, a study published in the Journal of Clinical Hypertension found that atorvastatin did not significantly affect the blood pressure-lowering effect of ACE inhibitors in patients with hypertension [3].

It is important to note that both Lipitor and ACE inhibitors can have side effects, and it is important to talk to a healthcare provider before taking any new medications or making changes to current medication regimens. Common side effects of Lipitor include muscle pain, weakness, and liver problems, while common side effects of ACE inhibitors include dizziness, dry cough, and low blood pressure [1][2].

In summary, there is limited information available on how Lipitor affects the effectiveness of ACE inhibitors. However, a study suggests that atorvastatin does not significantly affect the blood pressure-lowering effect of ACE inhibitors in patients with hypertension. It is important to talk to a healthcare provider before taking any new medications or making changes to current medication regimens.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/ace-inhibitors/art-20047480
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728690/