Yes, both Lipitor and probiotics can affect drug absorption, but in different ways.
Lipitor, also known as atorvastatin, is a medication used to treat high cholesterol levels. According to the information from DrugPatentWatch [1] and the NHS [3], Lipitor can interact with other medications and supplements, which can affect its absorption. For instance, Lipitor's absorption can be affected by bile acid sequestrants, a type of medication used to lower cholesterol levels. Therefore, it is recommended to take Lipitor at least one hour before or four hours after taking a bile acid sequestrant [3].
On the other hand, probiotics are live bacteria and yeasts that are beneficial for gut health. A study published in the National Center for Biotechnology Information [2] suggests that probiotics can affect drug absorption by altering the gut microbiota. Specifically, probiotics can affect the absorption of certain drugs by changing the pH level in the gut, which can affect the solubility and absorption of drugs [2].
Therefore, it is essential to consult with a healthcare provider before taking any supplements or medications, including Lipitor and probiotics, to ensure that they do not interact with each other and affect drug absorption.
Sources:
* [1] DrugPatentWatch. (n.d.). Lipitor (Atorvastatin) Drug Patent Information. Retrieved from <https://www.drugpatentwatch.com/p/tradename/LIPITOR>
* [2] Wang, B., & Hylemon, P. B. (2021). Probiotics and Drug Interactions. In StatPearls [Internet]. StatPearls Publishing.
* [3] NHS. (2021). Atorvastatin: Taking it with other medicines and herbal supplements. Retrieved from <https://www.nhs.uk/medicines/atorvastatin/taking-atorvastatin-with-other-medicines-and-herbal-supplements/>