Lipitor is a brand name for the drug atorvastatin, which is used to lower cholesterol levels in the body. Grapefruit juice is known to interact with certain medications, including statins like Lipitor. According to the drug patent information [1], Lipitor is metabolized by the liver enzyme CYP3A4. Grapefruit juice can inhibit this enzyme, which can lead to higher levels of Lipitor in the bloodstream and an increased risk of side effects.

The Harvard Health Publishing website [2] states that consuming grapefruit juice can increase the risk of side effects from Lipitor, such as muscle pain, liver damage, and an increased risk of rhabdomyolysis (a potentially life-threatening condition in which muscle fibers break down and release a protein into the bloodstream). The website advises patients taking Lipitor to avoid consuming grapefruit juice or to limit their intake to no more than one small glass per day.

The website Ro [3] also advises patients taking Lipitor to avoid consuming grapefruit juice. It states that the interaction between grapefruit juice and Lipitor can last for up to 72 hours after consuming the juice, and that patients should consult with their healthcare provider before consuming any grapefruit products while taking Lipitor.

In summary, grapefruit juice can interact with Lipitor and increase the risk of side effects. Patients taking Lipitor should avoid consuming grapefruit juice or limit their intake to no more than one small glass per day. They should also consult with their healthcare provider before consuming any grapefruit products while taking Lipitor.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.health.harvard.edu/heart-health/grapefruit-juice-and-statins
[3] https://ro.co/health-guide/lipitor-and-grapefruit/