Mixing alcohol with certain medications can lead to harmful interactions. Alcohol can increase or decrease the effects of medications, making them less effective or more potent. According to the National Institute on Alcohol Abuse and Alcoholism [2], alcohol can interact with medications that treat anxiety, depression, sleep disorders, and pain. The interactions can lead to increased drowsiness, dizziness, and impaired coordination, which can be dangerous while driving or operating machinery.

The website Drug Patent Watch [1] lists several medications that should not be mixed with alcohol. For example, alcohol can increase the risk of liver damage when taken with acetaminophen, which is found in many pain relievers. Alcohol can also increase the risk of bleeding when taken with blood thinners like warfarin.

GoodRx [3] also lists medications that should not be mixed with alcohol, including antibiotics like metronidazole and antihistamines like diphenhydramine. Mixing alcohol with these medications can cause nausea, vomiting, and headaches.

It is important to always read the label on medications and ask a healthcare provider or pharmacist if it is safe to drink alcohol while taking them. It is also important to be aware of the signs of harmful interactions, such as dizziness, confusion, and difficulty breathing. If these symptoms occur, seek medical attention immediately.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ALCOHOL
[2] https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/harmful-interactions-mixing-alcohol-with-medicines
[3] https://www.goodrx.com/drugs/side-effects/10-medications-you-shouldnt-mix-with-alcohol