After reviewing the available information, it is advised not to take Lipitor with grapefruit juice due to potential adverse effects.

Lipitor, a medication used to treat high cholesterol, can interact with certain substances, including grapefruit juice. This interaction can lead to increased levels of Lipitor in the bloodstream, which may increase the risk of side effects [1].

The active ingredient in Lipitor, atorvastatin, is metabolized in the body by enzymes, one of which is CYP3A4 [1]. Grapefruit juice contains furanocoumarins, which can inhibit the CYP3A4 enzyme, leading to increased levels of atorvastatin in the body [2].

The impact of grapefruit juice on Lipitor can vary depending on several factors, such as the amount of juice consumed, the timing of consumption, and individual genetic factors [2]. However, it is generally recommended to avoid consuming grapefruit juice while taking Lipitor as a precautionary measure.

In summary, consuming Lipitor with grapefruit juice can lead to increased levels of Lipitor in the bloodstream, potentially increasing the risk of side effects. It is advised to avoid consuming grapefruit juice while taking Lipitor [1][2].

Sources:
[1] <https://www.drugs.com/drug-interactions/atorvastatin-with-grapefruit-juice-4333-2.html>
[2] <https://www.drugpatentwatch.com/drugs/lipitor/interactions>