There is no definitive scientific evidence to suggest that swimming directly impacts the effectiveness of Lipitor (atorvastatin), a medication used to treat high cholesterol levels. Lipitor works by reducing the production of cholesterol in the body, and its effectiveness is generally not influenced by physical activities like swimming [1].

However, engaging in regular physical exercise like swimming can help lower cholesterol levels and improve overall heart health [2]. This can contribute to the management of high cholesterol and may reduce the reliance on medication. It is essential to consult with a healthcare provider before making any changes to a medication regimen or exercise routine.

Sources:

1. [Drugs.com](https://www.drugs.com/lipitor.html)
2. [American Heart Association](https://www.heart.org/en/healthy-living/fitness/why-is-physical-activity-so-important-for-overall-health-and-wellbeing)
3. [DrugPatentWatch.com](https://www.drugpatentwatch.com/drugs/lipitor)