Lipitor, a statin medication used to lower cholesterol levels, has been associated with potential negative effects on the liver. According to the Mayo Clinic, statins can cause an increase in liver enzymes, which can be a sign of liver damage [3]. However, it's important to note that this effect is usually mild and reversible [3].

The drugwatch.com website states that Lipitor has been linked to cases of liver damage, including liver failure, but these instances are considered rare [2]. The website also mentions that the FDA has received reports of severe liver injury in patients taking Lipitor, but the number of cases is not specified [2].

The Drug Patent Watch website provides information on Lipitor's patents and does not include specific details about the drug's negative effects on the liver [1].

In summary, Lipitor has been associated with potential negative effects on the liver, including an increase in liver enzymes and, in rare cases, liver damage or failure. It is important for individuals taking Lipitor to be monitored by a healthcare professional for any signs of liver problems.

Sources:
[1] <https://www.drugpatentwatch.com/p/tradename/LIPITOR>
[2] <https://www.drugwatch.com/lipitor/side-effects/>
[3] <https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013>