Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. According to the sources provided, Lipitor can be taken with or without food, as it does not affect the effectiveness of the medication [2][3]. However, it is recommended to take Lipitor at the same time every day, with a glass of water, and to avoid drinking grapefruit juice while taking this medication [2]. Grapefruit juice can increase the amount of Lipitor in the blood, leading to a higher risk of side effects [2]. It is important to follow the dosage instructions provided by the doctor or pharmacist and not to exceed the recommended dose [2][3]. If a dose is missed, it should be taken as soon as remembered, unless it is close to the next scheduled dose, in which case the missed dose should be skipped [2]. As with any medication, it is important to consult with a healthcare professional before taking Lipitor, especially if there are any concerns or questions about how to take it [2][3].

Sources:
[2] https://www.nhs.uk/medicines/atorvastatin/how-and-when-to-take-atorvastatin/
[3] https://www.drugs.com/medical-answers/eat-food-taking-atorvastatin-3565628/
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR