According to the sources provided, there is some evidence to suggest that Lipitor (atorvastatin) may lower vitamin D levels in some patients.
A study published in the Journal of Clinical Endocrinology and Metabolism [2] found that atorvastatin use was associated with a modest decrease in vitamin D levels in patients with type 2 diabetes. The study concluded that atorvastatin may interfere with vitamin D metabolism and recommended that vitamin D levels be monitored in patients taking atorvastatin.
Another study published in the International Journal of Endocrinology [3] also found that atorvastatin use was associated with lower vitamin D levels in patients with type 2 diabetes. The study suggested that atorvastatin may interfere with vitamin D synthesis and recommended that vitamin D supplementation be considered for patients taking atorvastatin.
However, it is important to note that not all studies have found a significant association between atorvastatin use and lower vitamin D levels. A review of several studies published in Drug Metabolism and Pharmacokinetics [1] found that while some studies have reported lower vitamin D levels in patients taking atorvastatin, others have not found a significant association.
In conclusion, while there is some evidence to suggest that atorvastatin may lower vitamin D levels in some patients, further research is needed to fully understand the relationship between atorvastatin use and vitamin D levels. Patients taking atorvastatin should talk to their healthcare provider about monitoring their vitamin D levels and potentially supplementing if necessary.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://pubmed.ncbi.nlm.nih.gov/17398180/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644425/