Lipitor is a prescription medication used to treat high cholesterol. It works by blocking an enzyme in the liver that produces cholesterol. According to the sources provided, there is no direct interaction between Lipitor and oranges. However, it is recommended to avoid consuming large amounts of grapefruit or grapefruit juice while taking Lipitor [2]. This is because grapefruit can interfere with the liver's ability to metabolize the medication, leading to higher levels of the drug in the bloodstream, which can increase the risk of side effects [2]. Oranges do not have the same effect as grapefruit, and there is no evidence to suggest that they would interfere with the effectiveness of Lipitor [3]. It is always important to consult with a healthcare provider before making any changes to your medication or diet [3].

In summary, there is no direct interaction between Lipitor and oranges. However, it is recommended to avoid consuming large amounts of grapefruit or grapefruit juice while taking Lipitor. As always, it is important to consult with a healthcare provider before making any changes to your medication or diet.

Sources:
[2] https://www.healthline.com/health/high-cholesterol/grapefruit-and-statins
[3] https://www.webmd.com/drugs/2/drug-3330/lipitor-oral/details/list-interaction-food