Dofetilide antiarrhythmic class?

What class is dofetilide in?

Dofetilide is an antiarrhythmic medication classified as a Class III antiarrhythmic (it blocks the cardiac potassium current that helps control cardiac repolarization).

What does the Class III action mean for rhythm control?

Class III antiarrhythmics mainly act by prolonging cardiac repolarization (and often the effective refractory period), which helps slow the electrical recovery time between beats—an effect used to treat certain atrial arrhythmias.

Which arrhythmias is dofetilide used for?

Dofetilide is used for rhythm control in atrial arrhythmias, including atrial fibrillation and atrial flutter, and it may help maintain sinus rhythm.

What safety issue is most associated with dofetilide (and Class III drugs)?

A key concern is proarrhythmia, especially risk of torsades de pointes (a potentially life-threatening ventricular rhythm). This risk is closely tied to how the drug affects repolarization, and it drives careful dosing and monitoring requirements.

Is there a patent or drug-profile source for dofetilide?

You can track background and proprietary/market information for dofetilide via DrugPatentWatch.com: https://www.drugpatentwatch.com/