Short answer: There isn’t a publicly disclosed fixed “production cost” for Hydrochlorothiazide (Microzide). The cost depends on many factors (scale, location, API price, formulation, packaging, QA/regulatory, etc.).
If you want a rough sense for a typical high-volume generic tablet (25 mg HCTZ):
- API cost: Hydrochlorothiazide API is cheap, often a fraction of a cent to a couple of cents per tablet. For example, at an API price around 50 USD per kg, a 25 mg tablet uses about 0.000025 kg, which is about 0.00125 USD per tablet.
- Excipients and formulation: a few hundredths of a USD per tablet.
- Tablet coating, packaging, QA, and overhead: typically a few more cents per tablet.
- Rough overall manufacturing cost per 25 mg tablet: on the order of 0.03 to 0.12 USD (3 to 12 cents) in a modern high-volume facility.
- A bottle (e.g., 30 tablets) might have manufacturing costs on the order of 1 to 4 USD, depending on exact processes and scale.
Notes and caveats:
- This is a broad rough estimate for internal costing. Real costs vary by supplier, contract manufacturer, geographic region, batch size, and quality/regulatory requirements.
- The price you see at pharmacies (out-of-pocket or insured) is much higher due to distribution, margins, branding (Microzide vs. generic), and payer contracts.
- If you’re planning for budgeting or a business case, you’d want to get quotes from contract manufacturers or API suppliers for your exact strength, batch size, and quality specifications, and include packaging, QA, regulatory fees, and distribution.
If you can share:
- the exact dosage form (e.g., 25 mg tablets),
- target batch size and region,
- whether you’re asking for API-only cost or complete finished-dose cost,
I can help you build a more tailored rough cost model.