Based on the available information, there can be side effects associated with long-term Vascepa use. According to Medical News Today, common side effects of Vascepa include joint pain, upset stomach, and changes in taste [2]. Healthline also mentions these side effects and adds that some people may experience allergic reactions, which can cause symptoms such as rash, itching, or hives [3].

It's important to note that the long-term side effects of Vascepa are not well-studied, as the drug is relatively new. The drug's patent information on Drug Patent Watch indicates that it was approved by the FDA in 2012 [1]. Therefore, more research is needed to fully understand the potential side effects of long-term use.

In conclusion, while there are known side effects associated with Vascepa use, the long-term side effects are not well-studied. As with any medication, it's important to discuss the potential risks and benefits with a healthcare provider.

Sources:
[1] <https://www.drugpatentwatch.com/p/tradename/VASCEPA>
[2] <https://www.medicalnewstoday.com/articles/drugs-vascepa-side-effects>
[3] <https://www.healthline.com/health/drugs/vascepa-side-effects>