Based on the available information, there is no explicit statement or evidence suggesting that live vaccines are unsafe with Cosentyx (secukinumab) use. However, it is important to note that the Cosentyx website states that "the safety and efficacy of Cosentyx in individuals with a chronic infection or a history of chronic or recurrent infection has not been established" [${2}].
Furthermore, a study published in the National Center for Biotechnology Information (NCBI) states that "IL-17A and IL-23 play a crucial role in the immune response against extracellular bacterial and fungal infections" [${3}]. Cosentyx is a monoclonal antibody that selectively binds to IL-17A and inhibits its interaction with the IL-17 receptor [${1}]. Therefore, it is possible that Cosentyx may affect the immune response to live vaccines.
In general, the Centers for Disease Control and Prevention (CDC) recommends that individuals taking immunosuppressive drugs should avoid live vaccines [${3}]. Therefore, it is crucial to consult with a healthcare provider before receiving any vaccinations while on Cosentyx.
In summary, while there is no explicit statement or evidence suggesting that live vaccines are unsafe with Cosentyx use, it is important to consult with a healthcare provider before receiving any vaccinations while on Cosentyx, as the drug may affect the immune response to live vaccines.
Sources:
* [Cosentyx](https://www.drugpatentwatch.com/p/biologics/tradename/COSENTYX)
* [Cosentyx and COVID-19](https://www.cosentyx.com/all/covid19)
* [IL-17A in Infectious Diseases](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767096/)