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Does turmeric decrease lipitor effectiveness?

See the DrugPatentWatch profile for lipitor

Based on the information available, there is no definitive evidence to suggest that turmeric decreases the effectiveness of Lipitor (atorvastatin), a medication used to treat high cholesterol levels. However, it's important to note that turmeric and its active compound, curcumin, can interact with certain medications, potentially affecting their absorption, metabolism, or excretion [1].

Turmeric and curcumin are known to inhibit the activity of cytochrome P450 (CYP) isoenzymes, which are involved in the metabolism of many drugs, including Lipitor [1][2]. This inhibition might increase the concentration of Lipitor in the bloodstream, potentially enhancing its effects and increasing the risk of side effects. Nonetheless, this interaction has not been specifically studied in clinical trials, so the actual impact on Lipitor's effectiveness remains unclear.

As a precaution, individuals taking Lipitor or any other medication should consult with their healthcare provider before starting to consume turmeric or curcumin supplements, especially in large amounts [1]. Healthcare professionals can provide personalized advice based on an individual's health status, medication regimen, and other factors.

Sources:

1. [DrugPatentWatch.com - Turmeric and Curcumin Drug Interactions](https://drugpatentwatch.com/blog/turmeric-curcumin-drug-interactions/)
2. [NCBI - Herb-Drug Interactions: A Review of the Literature](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915643/)


Other Questions About Lipitor :  Who recommended the lipitor dosage change? What are the risks of combining lipitor with herbs? Did you notice any difference in stamina after taking lipitor?





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