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See the DrugPatentWatch profile for Penicillin
Penicillin V (phenoxymethylpenicillin) is the oral form of penicillin. It works best against susceptible Gram-positive bacteria (especially streptococci) and is not reliable against beta-lactamase–producing organisms or many Gram‑negatives. Common uses: - Infections caused by susceptible streptococci - Acute streptococcal pharyngitis/tonsillitis - Scarlet fever - Erysipelas and nonpurulent cellulitis due to streptococci - Odontogenic (dental) and orofacial infections - Some mild to moderate skin and soft tissue infections due to streptococci - Prophylaxis - Secondary prophylaxis for rheumatic fever - Endocarditis prophylaxis in select high‑risk patients undergoing dental/respiratory procedures (when penicillin G/amoxicillin are unsuitable), per local guidelines Notes: - Not effective against beta-lactamase–producing organisms (e.g., many strains of Staphylococcus aureus, Haemophilus influenzae with beta-lactamase, Moraxella, many Gram‑negatives). - For infections caused by resistant organisms or beta-lactamase producers, alternatives such as amoxicillin-clavulanate or other agents are used. - Always use as directed by a clinician and follow local guidelines for dosing and duration. If penicillin allergy is present, alternatives should be considered.
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