Skyrizi dosing schedule?

What is Skyrizi’s usual dosing schedule for plaque psoriasis?

Skyrizi (risankizumab) dosing depends on the condition being treated, but for moderate-to-severe plaque psoriasis the typical schedule is an injection at weeks 0 and 4, then every 12 weeks after that. [1]

How often do injections happen after the first doses?

After the initial loading doses (week 0 and week 4), patients move to maintenance dosing every 12 weeks. [1]

What are the injection days (week numbers) patients usually follow?

For plaque psoriasis, the commonly followed calendar is:
- Week 0: first injection
- Week 4: second injection
- Week 16 onward: every 12 weeks
This pattern matches “every 12 weeks” maintenance after the initial two-dose start. [1]

What if you miss a dose?

The dosing schedule is built around fixed week intervals (weeks 0, 4, then every 12 weeks). If you miss a planned injection, the exact next step depends on how late the dose is and what your clinician advises, since the schedule is tied to the loading-to-maintenance transition. [1]

Sources

1. https://www.drugs.com/dosage/skyrizi.html