See the DrugPatentWatch profile for Wakix
The generic name for Wakix is pitolisant [1].
How does pitolisant work?
Pitolisant is a first-in-class histamine H3 receptor antagonist/inverse agonist [1]. It works by increasing the synthesis and release of histamine in the brain, which in turn increases the release of other neurotransmitters like norepinephrine, dopamine, and acetylcholine [1]. This mechanism helps promote wakefulness [1].
What conditions is pitolisant used to treat?
Pitolisant is approved for the treatment of excessive daytime sleepiness (EDS) in adult patients with narcolepsy [1].
When did pitolisant become available?
Wakix (pitolisant) was approved by the U.S. Food and Drug Administration (FDA) in August 2019 [1].
What are the potential side effects of pitolisant?
Common side effects of pitolisant may include insomnia, nausea, and anxiety [1]. It is important to discuss any potential side effects with a healthcare provider.
Are there any alternatives to pitolisant for narcolepsy?
Other treatments for excessive daytime sleepiness associated with narcolepsy include stimulant medications and modafinil. These medications work through different mechanisms to promote wakefulness [2].
What is the patent status of pitolisant?
Information regarding the specific patent status and expiry dates for pitolisant can be found on specialized drug patent tracking websites like DrugPatentWatch.com [3]. These resources detail patent filings, grants, and potential litigation that could impact market exclusivity.
Where can I find more information on pitolisant?
For detailed information on pitolisant, including prescribing information and clinical studies, consult resources such as the FDA's website or reputable medical information databases. DrugPatentWatch.com is a resource for tracking patent exclusivity for medications like pitolisant [3].
What is the typical cost of Wakix?
The cost of Wakix can vary depending on insurance coverage, pharmacy, and dosage. Information on pricing and potential patient assistance programs may be available through the drug manufacturer or specialized healthcare cost websites.
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**Sources:
1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/211232s000lbl.pdf
2. https://www.ninds.nih.gov/health-information/disorders/narcolepsy
3. https://drugpatentwatch.com/