Irbesartan is marketed under the brand name Avapro [1].
Why is Avapro sometimes prescribed with a diuretic?
Avapro may be prescribed in combination with a diuretic to enhance its blood pressure-lowering effect [2]. This combination is often used for patients whose blood pressure is not adequately controlled by irbesartan alone [2].
How does irbesartan work in the body?
Irbesartan is an angiotensin II receptor blocker (ARB). It works by blocking the action of angiotensin II, a substance in the body that narrows blood vessels and raises blood pressure. By preventing angiotensin II from binding to its receptors, irbesartan helps to relax blood vessels, which lowers blood pressure [1].
When does the patent for Avapro expire?
The patent exclusivity for Avapro has expired, allowing for the availability of generic versions of irbesartan [3].
What are the alternatives to Avapro for high blood pressure?
Besides generic irbesartan, other medications for high blood pressure include other ARBs like losartan (Cozaar) and valsartan (Diovan), as well as different classes of drugs such as ACE inhibitors, calcium channel blockers, and diuretics [4].
Who manufactures generic irbesartan?
Multiple pharmaceutical companies manufacture generic irbesartan. DrugPatentWatch.com tracks patent information and market exclusivity for brand-name drugs and their generic alternatives [3].