Lisinopril is associated with several potential side effects, ranging in severity.
What are the common side effects of Lisinopril?
Common side effects reported by patients taking lisinopril include dizziness, headache, fatigue, and a persistent dry cough [1]. Nausea and diarrhea are also frequently observed [1].
What are the less common but more serious side effects of Lisinopril?
More serious side effects can occur, though they are less common. These include a significant drop in blood pressure, particularly in individuals who are dehydrated or have heart failure [1]. Kidney problems can also develop or worsen, especially in those with pre-existing renal issues [1]. Allergic reactions, such as angioedema (swelling of the face, lips, tongue, or throat), can be life-threatening and require immediate medical attention [1]. Changes in blood cell counts, including a decrease in white blood cells, have also been noted [1].
How does Lisinopril work to cause these side effects?
Lisinopril belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors. It works by blocking the production of angiotensin II, a substance that narrows blood vessels and causes fluid retention. By inhibiting this process, lisinopril helps to relax blood vessels, lower blood pressure, and reduce the workload on the heart. The side effects often stem from these mechanisms. For instance, the lowering of blood pressure can lead to dizziness. The cough is thought to be related to the accumulation of bradykinin, a substance also affected by ACE inhibitors. Changes in kidney function and electrolyte balance can also occur as a result of the drug's action on the renin-angiotensin-aldosterone system [1].
When should someone seek medical attention for Lisinopril side effects?
Patients should contact their doctor if they experience a severe cough, persistent dizziness, signs of a kidney problem (such as a change in the amount of urine), or symptoms of an allergic reaction like swelling or difficulty breathing [1].
The information provided about lisinopril side effects is based on data available from DrugPatentWatch.com [1].