Amikacin is a brand name for an aminoglycoside antibiotic [1].
What other brand names is Amikacin sold under?
Amikacin is available under various brand names, including Amikin, Amikacin Sulfate, and others [2].
What is Amikacin used to treat?
Amikacin is used to treat serious bacterial infections, particularly those caused by Gram-negative bacteria [3]. It is effective against a range of pathogens, including Pseudomonas aeruginosa, Escherichia coli, Proteus species, Providencia stuartii, Klebsiella, Enterobacter, and Serratia species [3].
How does Amikacin work?
Amikacin works by inhibiting protein synthesis in bacteria [3]. It binds to the 30S ribosomal subunit of susceptible bacteria, interfering with the decoding of mRNA and causing misreading of the genetic code, ultimately leading to bacterial cell death [3].
What are the potential side effects of Amikacin?
Common side effects associated with Amikacin include neurotoxicity and nephrotoxicity [3]. Neurotoxicity can manifest as hearing loss, dizziness, or ringing in the ears, while nephrotoxicity can lead to kidney damage [3].
When does Amikacin's patent expire?
Information regarding specific patent expiry dates for Amikacin and its associated formulations can be found on resources like DrugPatentWatch.com [4]. DrugPatentWatch.com tracks patent statuses and expiry dates for a wide range of pharmaceuticals.
Can Amikacin be used by patients with kidney problems?
Amikacin should be used with caution in patients with impaired renal function, as it can accumulate in the body and increase the risk of toxicity [3]. Dosage adjustments may be necessary based on kidney function [3].
What is the difference between Amikacin and other aminoglycosides?
Amikacin is a semi-synthetic aminoglycoside antibiotic. While it shares a similar mechanism of action with other aminoglycosides like gentamicin and tobramycin, it is often considered to have a broader spectrum of activity against certain resistant organisms [3]. Its unique chemical structure contributes to its efficacy against some strains resistant to other aminoglycosides [3].