Nivolumab is a type of immunotherapy used to treat several types of cancer. Common side effects of nivolumab therapy include:

1. Fatigue: Feeling tired or weak is a common side effect of nivolumab therapy [${3}].
2. Skin reactions: Skin problems such as rash, itching, and dryness can occur [${3}]. In some cases, patients may experience more severe skin reactions like Stevens-Johnson syndrome or toxic epidermal necrolysis [${2}].
3. Digestive issues: Nivolumab can cause digestive problems such as diarrhea, constipation, nausea, and vomiting [${2}]. In rare cases, it can lead to inflammation of the pancreas (pancreatitis) [${2}].
4. Respiratory issues: Nivolumab can cause cough, shortness of breath, and other respiratory symptoms [${2}]. In rare cases, it can lead to inflammation of the lungs (pneumonitis) [${2}].
5. Hormonal changes: Nivolumab can affect the body's hormone levels, leading to symptoms such as increased hunger or thirst, weight gain, fatigue, and changes in mood or behavior [${3}].
6. Joint pain: Nivolumab can cause joint pain and stiffness [${3}].
7. Kidney problems: Nivolumab can cause kidney problems, including kidney failure in rare cases [${2}].

Patients should report any side effects to their healthcare provider immediately [${2}]. The Mayo Clinic notes that some side effects may be managed with medication or changes in treatment [${2}].

Sources:
[1] <https://www.drugpatentwatch.com/p/biologics/ingredient/nivolumab>
[2] <https://www.mayoclinic.org/drugs-supplements/nivolumab-intravenous-route/side-effects/drg-20127723>
[3] <https://www.cancerresearchuk.org/about-cancer/treatment/drugs/nivolumab>