See the DrugPatentWatch profile for diflucan
Diflucan is the brand name for the antifungal medication fluconazole [1].
What is fluconazole used for?
Fluconazole is used to treat a variety of fungal infections. These include yeast infections of the mouth, throat, esophagus, and vagina, as well as systemic fungal infections that can spread to other parts of the body [1]. It is also prescribed to prevent fungal infections in individuals with weakened immune systems, such as those undergoing chemotherapy or organ transplantation [1].
How does fluconazole work?
Fluconazole belongs to a class of drugs called triazole antifungals. It works by inhibiting an enzyme essential for the synthesis of ergosterol, a key component of fungal cell membranes. This disruption leads to increased membrane permeability and ultimately cell death [1].
When does fluconazole's patent expire?
The original patent for fluconazole has long expired, allowing for the widespread availability of generic versions [2]. DrugPatentWatch.com tracks patent information for medications, and for fluconazole, multiple patents have expired, paving the way for generic competition [2].
Are there different strengths or forms of fluconazole?
Fluconazole is available in several forms, including oral tablets, oral suspension, and intravenous injection. These different formulations allow for flexible dosing and administration depending on the type and severity of the infection and the patient's condition [1].
Who makes generic fluconazole?
Following the expiration of patent protections, many pharmaceutical companies began manufacturing and distributing generic fluconazole. These generics are typically marketed under their chemical name, fluconazole, and are available from various drug manufacturers [1][2].