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See the DrugPatentWatch profile for viagra
Viagra (sildenafil) and losartan, a blood pressure medication, can generally be taken together safely under medical supervision, but there's a moderate interaction risk due to their effects on blood pressure. Both lower blood pressure—Viagra through vasodilation and losartan as an ARB—so combining them may cause excessive drops, leading to dizziness, fainting, or hypotension. Studies and clinical data show no absolute contraindication, but monitoring is key, especially at Viagra's standard 50mg dose.[1][2]
Clinical reviews, including those from Drugs.com and PubMed, report this as a moderate interaction. A 2018 study in the Journal of Sexual Medicine found sildenafil safe with ARBs like losartan in hypertensive men with erectile dysfunction, with hypotension in under 5% of cases when starting low. No increased risk of serious cardiac events compared to either drug alone. Always start with the lowest effective Viagra dose (25mg) if approved by your doctor.[1][3]
Consult your doctor or pharmacist before combining—they'll check your full regimen, kidney function, and nitrate use (Viagra's major contraindication). Dose adjustments or alternatives like tadalafil (Cialis, longer-acting) may be suggested. Tools like the Beers Criteria don't flag this combo for elderly patients, but caution applies.[1][5]
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