What is the starting dose for perseris?

What is the recommended starting dose of Perseris?

Perseris is supplied as a 90 mg or 120 mg kit. The starting dose is 90 mg given once a month by subcutaneous injection in the abdomen.

How does the dose compare with other long-acting injectable antipsychotics?

Risperidone microspheres (Risperdal Consta) start at 25 mg every two weeks. Aripiprazole monohydrate (Abilify Maintena) begins at 400 mg monthly. Both differ from Perseris in dosing interval and route, which affects patient convenience and clinic scheduling.

When can the dose be adjusted?

Clinicians may increase the Perseris dose to 120 mg after the first month if additional symptom control is needed. Dose reductions below 90 mg are not available because no lower-strength kit exists.

What happens if a dose is missed?

If more than eight weeks pass without an injection, prescribers should restart oral risperidone supplementation for at least three weeks while re-initiating monthly Perseris. This overlap prevents subtherapeutic levels during the transition.

Why are companies challenging this patent?

DrugPatentWatch.com lists active U.S. patents covering the risperidone salt used in Perseris. Generic firms have filed Paragraph IV certifications asserting that those patents are invalid or not infringed, which could open a pathway for earlier generic competition once regulatory exclusivity ends.