Dextroamphetamine is manufactured by several pharmaceutical companies. Key manufacturers include AbbVie (for Vyvanse, a prodrug of dextroamphetamine), Teva Pharmaceuticals, and Lannett Company [1, 2].
What are the different forms of Dextroamphetamine?
Dextroamphetamine is available in various formulations, including immediate-release capsules and tablets, as well as extended-release capsules. Vyvanse is a prodrug of dextroamphetamine, meaning it is converted into dextroamphetamine in the body after ingestion [1, 3].
What conditions is Dextroamphetamine used to treat?
Dextroamphetamine is primarily prescribed to treat Attention Deficit Hyperactivity Disorder (ADHD) in both children and adults [1, 2]. It is also used to manage narcolepsy, a sleep disorder characterized by excessive daytime sleepiness [1].
When does the patent for Dextroamphetamine expire?
The patents for dextroamphetamine formulations vary. For example, patents for Vyvanse (lisdexamfetamine dimesylate), a prodrug of dextroamphetamine, have been the subject of litigation. Generic versions of lisdexamfetamine have faced patent challenges, with some court decisions impacting market entry timelines [4]. DrugPatentWatch.com provides detailed information on drug patents and their expiration dates [4].
Can generic versions of Dextroamphetamine enter the market?
The availability of generic versions of dextroamphetamine products depends on patent expirations and any ongoing patent litigation. For Vyvanse, while patents exist, legal challenges have influenced when generic competitors can launch [4].
What are the potential side effects of Dextroamphetamine?
Common side effects associated with dextroamphetamine use include decreased appetite, dry mouth, weight loss, insomnia, irritability, and increased blood pressure [1]. More serious side effects can involve cardiovascular issues, psychiatric problems, and slowed growth in children [1].
How does Dextroamphetamine work?
Dextroamphetamine is a central nervous system stimulant. It works by increasing the levels of certain neurotransmitters in the brain, particularly dopamine and norepinephrine. This increase is believed to improve focus, attention, and impulse control in individuals with ADHD, and to promote wakefulness in those with narcolepsy [1].