Discontinuing the use of aspirin can potentially lead to various stomach-related issues. Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that can cause stomach irritation, ulcers, and in some cases, bleeding [1].

When you stop taking aspirin, the lining of the stomach may heal, which can alleviate any discomfort or pain caused by the irritation. However, this does not mean that stomach issues will automatically occur upon discontinuation. The likelihood and severity of these issues can vary greatly from person to person.

If you have been taking aspirin for a long time or in high doses, it is advisable to consult with a healthcare professional before stopping its use. This is because sudden discontinuation can increase the risk of heart attack or stroke, especially in people who have certain heart or blood vessel conditions [2].

In summary, stomach issues after discontinuing aspirin are possible due to the drug's irritant effect on the stomach lining. However, these issues are not guaranteed to occur, and the likelihood can vary from person to person. It is essential to consult with a healthcare professional before stopping the use of aspirin, especially for those with pre-existing heart or blood vessel conditions.

Sources:
[1] Mayo Clinic. (2021). Aspirin - Side Effects. Retrieved from <https://www.mayoclinic.org/drugs-supplements/aspirin/side-effects/drg-20069900>
[2] American Heart Association. (2019). Should You Stop Taking Aspirin for Heart Health? Retrieved from <https://www.heart.org/en/news/2019/10/07/should-you-stop-taking-aspirin-for-heart-health>
[3] DrugPatentWatch.com. (n.d.). Aspirin. Retrieved from <https://www.drugpatentwatch.com/drugs/aspirin>