Dupixent pen instructions?

Here are the general instructions for using the Dupixent (dupilumab) Pen. (Because instructions can vary a bit by country/device version, I’ll also note where to follow your exact prescription leaflet.)

1) Before you start

• Check the label: confirm it’s Dupixent and the dose your prescriber ordered.
• Store correctly: typically refrigerated (follow your package directions). Do not freeze.
• Let it warm: take the pen out and allow it to reach room temperature if your leaflet says to. (Cold injections can be more uncomfortable.)
• Inspect the solution: the medicine should be clear to slightly opalescent and colorless to pale yellow.
  • Do not use if it’s cloudy, colored, or has particles, or if the pen looks damaged.

2) What you need

• 1 Dupixent pre-filled pen
• Alcohol wipe (or similar) for skin cleaning
• Cotton/gauze if needed
• Sharps container for disposal

3) Choose an injection site

Use subcutaneous (under the skin) injection sites:

• Front of the thighs
• Abdomen (except within about 2 inches / 5 cm of the belly button)

Rotate sites each time. Avoid injecting into skin that’s tender, bruised, red, or scarred.

4) Injection steps (typical for the pen)

1. Wash hands.
2. Clean the injection site with an alcohol wipe and let it dry.
3. With your other hand, you may be instructed to hold and pinch the skin (varies by pen instructions; if your leaflet says to, do it).
4. Place the pen against the skin at the chosen site.
5. Press the pen firmly as instructed and activate the dose.
6. Keep the pen in place until the injection completes.
   • The pen usually provides visual/audible signals; follow those signals exactly.
7. Remove the pen and gently press a small piece of gauze if needed (don’t rub hard).

5) After the injection

• Dispose the pen immediately in a sharps container.
• If there’s bleeding, apply gentle pressure with gauze.
• Do not reuse the pen.

6) Missed dose (general guidance)

• If you miss a dose, take it as soon as you remember—but don’t double up.
• If you’re close to the next dose, usually skip the missed one and continue your schedule.
• Best to follow your exact dosing instructions from your prescription/leaflet or ask your pharmacist.

7) Common things that cause problems

• Injecting into irritated or scarred skin
• Using a pen that is too cold
• Not holding/pressing the pen correctly until completion
• Not rotating sites

8) Important safety notes (seek care if)

Call your clinician urgently or seek emergency care if you have:

• Signs of serious allergic reaction (swelling of face/lips, trouble breathing, hives)
• Worsening eye symptoms (pain, redness, vision changes) — conjunctivitis/eye inflammation can occur
• Severe or persistent symptoms after dosing

Quick question so I can tailor the instructions:

Are you using the Dupixent pen for asthma, eczema, or nasal polyps, and do you know your dose (e.g., 200 mg every 2 weeks or 300 mg every 2 weeks)? Also, if you can, tell me what your pen label says (the exact wording can differ slightly by region).